Galactosylated cucurbituril-inclusion polyplex for hepatocyte-targeted gene delivery

被引：63

作者：

Kim, Soo Kyung ^{[3
]}

Park, Kyeng Min ^{[1
,2
]}

Singha, Kaushik ^{[3
]}

Kim, Jeeyeon ^{[1
,2
]}

Ahn, Youngjoo ^{[1
,2
]}

Kim, Kimoon ^{[1
,2
]}

Kim, Won Jong ^{[3
]}

机构：

[1] Pohang Univ Sci & Technol POSTECH, Natl Creat Res Initiat, Ctr Smart Supramol, Dept Chem, Pohang 790784, South Korea

[2] Pohang Univ Sci & Technol POSTECH, Div Adv Mat Sci, Pohang 790784, South Korea

[3] Pohang Univ Sci & Technol POSTECH, Dept Chem, Polymer Res Inst, Program BK21, Pohang 790784, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 05期

关键词：

TRANSFECTION; THERAPY; DISEASE; COMPLEX; DNA;

D O I：

10.1039/b920753h

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

The work demonstrates a judicious approach to achieve hepatocyte cell-targeted highly efficient gene delivery by utilizing a supramolecular complex of galactosylated cucurbituril and dextran-spermine conjugates.

引用

页码：692 / 694

页数：3

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