Genes involved in phenotypic and antigenic variation in African trypanosomes and malaria

被引：14

作者：

Rudenko, G ^{[1
]}

机构：

[1] Univ Oxford, Wellcome Trust Ctr Epidemiol Infect Dis, Dept Zool, Oxford OX1 3FY, England

来源：

CURRENT OPINION IN MICROBIOLOGY | 1999年 / 2卷 / 06期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S1369-5274(99)00039-9

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Large polymorphic gene families that are involved in clonal phenotypic variation have been identified in both African trypanosomes and malaria parasites. Many of these gene families are necessary for host adaptation, allowing the parasite to infect different species of host or types of host cells, in many cases, switching between these functionally variable proteins also results in antigenic variation.

引用

页码：651 / 656

页数：6

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