Antidepressant medications, mood and male fertility

被引：43

作者：

Hendrick, V ^{[1
]}

Gitlin, M

Altshuler, L

Korenman, S

机构：

[1] Univ Calif Los Angeles, Neuropsychiat Inst & Hosp, Los Angeles, CA 90095 USA

[2] W LA Vet Adm Med Ctr, Los Angeles, CA 90095 USA

[3] Univ Calif Los Angeles, Hlth Sci Ctr, Div Endocrinol, Los Angeles, CA 90095 USA

来源：

PSYCHONEUROENDOCRINOLOGY | 2000年 / 25卷 / 01期

关键词：

men; mood; fertility; antidepressants; androgens; reproductive functioning;

D O I：

10.1016/S0306-4530(99)00038-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

By modulating the activity of central neurotransmitters, psychotropic agents may affect reproductive functioning in men and women. Many neurotransmitters influence the hypothalamic-pituitary-gonadal (HPG) axis and can consequently affect menstrual cycling in women and spermatogenesis in men. Emotional state similarly may disrupt reproductive functioning through the effects of stress hormones on the HPG axis. While some data exist on the relationship between stress and menstrual cyclicity in women of reproductive age, little is known regarding the potential effect of emotional state on reproductive function in men. This paper will review: (1) aspects of male reproductive function that may be vulnerable to medication-induced influences: (2) the impact of emotional state on male reproductive function; and (3) the literature on the possible effects of antidepressant medications on male Fertility. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：37 / 51

页数：15

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