Antidepressant medications, mood and male fertility

被引：43

作者：

Hendrick, V ^{[1
]}

Gitlin, M

Altshuler, L

Korenman, S

机构：

[1] Univ Calif Los Angeles, Neuropsychiat Inst & Hosp, Los Angeles, CA 90095 USA

[2] W LA Vet Adm Med Ctr, Los Angeles, CA 90095 USA

[3] Univ Calif Los Angeles, Hlth Sci Ctr, Div Endocrinol, Los Angeles, CA 90095 USA

来源：

PSYCHONEUROENDOCRINOLOGY | 2000年 / 25卷 / 01期

关键词：

men; mood; fertility; antidepressants; androgens; reproductive functioning;

D O I：

10.1016/S0306-4530(99)00038-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

By modulating the activity of central neurotransmitters, psychotropic agents may affect reproductive functioning in men and women. Many neurotransmitters influence the hypothalamic-pituitary-gonadal (HPG) axis and can consequently affect menstrual cycling in women and spermatogenesis in men. Emotional state similarly may disrupt reproductive functioning through the effects of stress hormones on the HPG axis. While some data exist on the relationship between stress and menstrual cyclicity in women of reproductive age, little is known regarding the potential effect of emotional state on reproductive function in men. This paper will review: (1) aspects of male reproductive function that may be vulnerable to medication-induced influences: (2) the impact of emotional state on male reproductive function; and (3) the literature on the possible effects of antidepressant medications on male Fertility. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：37 / 51

页数：15

共 96 条

[21] EFFECTS OF ANDROGEN ON SEXUAL-BEHAVIOR IN HYPOGONADAL MEN [J].

DAVIDSON, JM ;

CAMARGO, CA ;

SMITH, ER .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1979, 48 (06) :955-958

[22] SALIVARY TESTOSTERONE LEVELS AND MAJOR DEPRESSIVE-ILLNESS IN MEN [J].

DAVIES, RH ;

HARRIS, B ;

THOMAS, DR ;

COOK, N ;

READ, G ;

RIADFAHMY, D .

BRITISH JOURNAL OF PSYCHIATRY, 1992, 161 :629-632

[23] COPING AND THE INEFFECTIVENESS OF COPING INFLUENCE THE OUTCOME OF INVITRO FERTILIZATION THROUGH STRESS RESPONSES [J].

DEMYTTENAERE, K ;

NIJS, P ;

EVERSKIEBOOMS, G ;

KONINCKX, PR .

PSYCHONEUROENDOCRINOLOGY, 1992, 17 (06) :655-665

[24] ANXIETY AND CONCEPTION RATES IN DONOR INSEMINATION [J].

DEMYTTENAERE, K ;

NIJS, P ;

STEENO, O ;

KONINCKX, P ;

EVERSKIEBOOMS, G .

JOURNAL OF PSYCHOSOMATIC OBSTETRICS AND GYNECOLOGY, 1988, 8 (03) :175-181

[25] CORTISOL-INDUCED SUPPRESSION OF PLASMA TESTOSTERONE IN NORMAL ADULT MALES [J].

DOERR, P ;

PIRKE, KM .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1976, 43 (03) :622-629

[26] A SUPPRESSION OF GONADOTROPIN-SECRETION BY CORTISOL IN CASTRATED MALE RHESUS-MONKEYS (MACACA-MULATTA) MEDIATED BY THE INTERRUPTION OF HYPOTHALAMIC GONADOTROPIN-RELEASING HORMONE-RELEASE [J].

DUBEY, AK ;

PLANT, TM .

BIOLOGY OF REPRODUCTION, 1985, 33 (02) :423-431

[27] STRESSFUL LIFE EVENTS AND AFFECTIVE-DISORDERS INHIBIT PULSATILE LH-SECRETION IN HYPOTHALAMIC AMENORRHEA [J].

FACCHINETTI, F ;

FAVA, M ;

FIORONI, L ;

GENAZZANI, AD ;

GENAZZANI, AR .

PSYCHONEUROENDOCRINOLOGY, 1993, 18 (5-6) :397-404

[28] An increased vulnerability to stress is associated with a poor outcome of in vitro fertilization-embryo transfer treatment [J].

Facchinetti, F ;

Matteo, ML ;

Artini, GP ;

Volpe, A ;

Genazzani, AR .

FERTILITY AND STERILITY, 1997, 67 (02) :309-314

[29] DEPRESSION AND ANXIETY ASSOCIATED WITH SECONDARY AMENORRHEA [J].

FAVA, GA ;

TROMBINI, G ;

GRANDI, S ;

BERNARDI, M ;

EVANGELISTI, LP ;

SANTARSIERO, G ;

ORLANDI, C .

PSYCHOSOMATICS, 1984, 25 (12) :905-908

[30]

FRANCIS AF, 1976, POSTGRAD MED J, V52, P81

← 1 2 3 4 5 6 7 8 9 10 →