Ferulagone:: A new monoterpene ester from Ferulago thirkeana essential oil

被引：27

作者：

Baser, KHC ^{[1
]}

Demirci, B

Demirci, F

Hashimoto, T

Asakawa, Y

Noma, Y

机构：

[1] Anadolu Univ, Med & Aromat Plant & Drug Res Ctr, TBAM, TR-26470 Eskisehir, Turkey

[2] Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 770, Japan

[3] Tokushima Bunri Univ, Fac Domest Sci, Tokushima, Japan

来源：

PLANTA MEDICA | 2002年 / 68卷 / 06期

关键词：

D O I：

10.1055/s-2002-32557

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Essential oil obtained by micro-distillation and hydrodistillation of the endemic Ferulago thirkeana (Boiss.) Boiss. (Apiaceae) was analysed by GC/MS. An unknown component isolated from the essential oil was characterized by chromato-spectral techniques (1D-, 2D-NMR, HRMS, IR and UV) as (1S)-2,6,6-trimethyl-4-oxobicyclo[3.1.1]hept-2-enyl(2E)-2-methylbut-2-enoate (= ferulagone or 1-angeloyloxyverbenone) (1). Biological activities of the essential oil and the purified major component (1) were tested against various human pathogenic microorganisms resulting in moderate inhibition (62.5-125 mug/ml).

引用

页码：564 / 567

页数：4

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[4]

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