RNA interference

被引：3221

作者：

Hannon, GJ ^{[1
]}

机构：

[1] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA

来源：

NATURE | 2002年 / 418卷 / 6894期

关键词：

D O I：

10.1038/418244a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A conserved biological response to double-stranded RNA, known variously as RNA interference (RNA) or post-transcriptional gene silencing, mediated resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes. RNAi has been cultivated as a means to manipulate gene expression experimentally and to probe gene function on a whole-genome scale.

引用

页码：244 / 251

页数：8

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