Folding DNA Origami from a Double-Stranded Source of Scaffold

被引:82
作者
Hogberg, Bjorn [1 ]
Liedl, Tim
Shih, William M.
机构
[1] Harvard Univ, Sch Med, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA
关键词
THERMODYNAMICS; FORMAMIDE; SHAPES;
D O I
10.1021/ja902569x
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Combined heat and chemical denaturation of double-stranded DNA scaffold strands in the presence of staple strands, followed by a sudden temperature drop and then stepwise dialysis to remove the chemical denaturant, leads to self-assembly of two distinct DNA-origami structures.
引用
收藏
页码:9154 / +
页数:3
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