Engineering a material for biomedical applications with electric field assisted processing

被引：34

作者：

Ahmad, Z. ^{[1
]}

Nangrejo, M. ^{[1
]}

Edirisinghe, M. ^{[1
]}

Stride, E. ^{[1
]}

Colombo, P. ^{[1
,2
,3
]}

Zhang, H. B. ^{[4
]}

机构：

[1] UCL, Dept Mech Engn, London WC1E 7JE, England

[2] Univ Padua, Dept Mech Engn & Mat Sci, I-35122 Padua, Italy

[3] Penn State Univ, Dept Mat Sci & Engn, University Pk, PA 16802 USA

[4] E China Univ Sci & Technol, Sch Mech & Power Engn, Shanghai 200237, Peoples R China

来源：

APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING | 2009年 / 97卷 / 01期

基金：

英国工程与自然科学研究理事会;

关键词：

POLYMER PARTICLES; DRUG-DELIVERY; ENCAPSULATION; FORMULATION; FABRICATION; NANOFIBERS; MEMBRANES; DESIGN; DROPS; SHAPE;

D O I：

10.1007/s00339-009-5359-z

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

In this work, using multiple co-flows we demonstrate in-situ encapsulation of nano-particles, liquids and/or gases in different structural morphologies, which can also be deposited in a designated pattern by a direct write method and surface modification can be controlled to release encapsulated material. The range of possibilities offered by exposing a material solution to an applied electric field can result in a plethora of structures which can accommodate a whole host of biomedical applications from microfluidic devices (microchannels, loaded with various materials), printed 3D structures and patterns, lab-on-a-chip devices to encapsulated materials (capsules, tubes, fibres, dense multi-layered fibrous networks) for drug delivery and tissue engineering. The structures obtained in this way can vary in size from micrometer to the nanometer range and the processing is viable for all states of matter. The work shown demonstrates some novel structures and methodologies for processing a biomaterial.

引用

页码：31 / 37

页数：7

共 27 条

[1] Generation of multilayered structures for biomedical applications using a novel tri-needle coaxial device and electrohydrodynamic flow [J].