A natural phosphate and doped-catalyzed Michael addition of mercaptans to α,β-unsaturated carbonyl compounds

被引：84

作者：

Abrouki, Y ^{[1
]}

Zahouily, M ^{[1
]}

Rayadh, A ^{[1
]}

Bahlaouan, B ^{[1
]}

Sebti, S ^{[1
]}

机构：

[1] Univ Hassan 2, Fac Sci & Tech, UFR Chim Appliquee, Lab Synthese Organ & Traitement Informat, Mohammadia 20650, Morocco

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 49期

关键词：

natural phosphate; potassium fluoride; heterogeneous catalysis; Michael addition; recyclable catalyst;

D O I：

10.1016/S0040-4039(02)02146-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The natural phosphate and doped by potassium fluoride catalyzed Michael addition of mercaptans to chalone derivatives with high yields in few minutes and under mild reaction conditions. Products of undesirable side reactions resulting from 1,2-addition, polymerisation and bis-addition are not observed. The work-up procedure is simplified by simple filtration with the use of natural phosphate alone or doped with potassium fluoride. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：8951 / 8953

页数：3

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