Cyclopropylboronic acid: synthesis and Suzuki cross-coupling reactions

被引：75

作者：

Wallace, DJ ^{[1
]}

Chen, CY ^{[1
]}

机构：

[1] Merck Res Labs, Dept Proc Res, Rahway, NJ 07065 USA

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 39期

关键词：

cyclopropylboronic acid; Suzuki cross-coupling; pharmaceutically acitve molecules;

D O I：

10.1016/S0040-4039(02)01606-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of cyclopropylboronic acid is reported. This compound undergoes efficient Suzuki-type coupling reactions with a range of aryl and heteroarybromides. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：6987 / 6990

页数：4

共 35 条

[1] Novel electron-rich bulky phosphine ligands facilitate the palladium-catalyzed preparation of diaryl ethers
Aranyos, A
Old, DW
Kiyomori, A
Wolfe, JP
Sadighi, JP
Buchwald, SL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (18) : 4369 - 4378
[2] New N- and O-arylations with phenylboronic acids and cupric acetate
Chan, DMT
Monaco, KL
Wang, RP
Winters, MP
[J]. TETRAHEDRON LETTERS, 1998, 39 (19) : 2933 - 2936
[3] Chemler SR, 2001, ANGEW CHEM INT EDIT, V40, P4544, DOI 10.1002/1521-3773(20011217)40:24<4544::AID-ANIE4544>3.0.CO
[4] 2-N
[5] CIMETIERE B, 1991, SYNLETT, P271
[6] A METHOD FOR THE STEREOSPECIFIC SYNTHESIS OF CHIRAL CIS-2-ALKYLCYCLOPROPYLLITHIUM REAGENTS
COREY, EJ
ECKRICH, TM
[J]. TETRAHEDRON LETTERS, 1984, 25 (23) : 2415 - 2418
[7] Convenient preparation of a cyclopropanation reagent: alpha-siloxymethyliron complex
Du, H
Yang, FK
Hossain, MM
[J]. SYNTHETIC COMMUNICATIONS, 1996, 26 (07) : 1371 - 1377
[8] Synthesis of diaryl ethers through the copper-promoted arylation of phenols with arylboronic acids. An expedient synthesis of thyroxine
Evans, DA
Katz, JL
West, TR
[J]. TETRAHEDRON LETTERS, 1998, 39 (19) : 2937 - 2940
[9] A CONVENIENT HIGHLY STEREOSELECTIVE SYNTHESIS OF CYCLOPROPYLBORONATES
FONTANI, P
CARBONI, B
VAULTIER, M
CARRIE, R
[J]. TETRAHEDRON LETTERS, 1989, 30 (36) : 4815 - 4818
[10] FONTANI P, 1991, SYNTHESIS-STUTTGART, P605

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