Synthesis of mono- and disubstituted sulfines via beta-elimination of chloroform from trichloromethyl sulfoxides

被引：11

作者：

Braverman, S

Grinstein, D

Gottlieb, HE

机构：

[1] Department of Chemistry, Bar-Ilan University

来源：

TETRAHEDRON | 1997年 / 53卷 / 40期

基金：

以色列科学基金会;

关键词：

D O I：

10.1016/S0040-4020(97)00904-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method for the synthesis of thioaldehyde and thioketone S-oxides by an unusual base-induced beta-elimination of chloroform from readily available allylic and benzylic trichloromethyl sulfoxides is described. The reaction proceeds smoothly under mild conditions. The facile preparation of alpha,beta-unsaturated sulfines by the new method is of special interest A possible mechanism for this remarkable sulfine synthesis and apparently unprecedented beta-elimination of chloroform is presented (C) 1997 Elsevier Science Ltd.

引用

收藏

页码：13933 / 13944

页数：12

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