Balancing acts: Molecular control of mammalian iron metabolism

被引：1481

作者：

Hentze, MW

Muckenthaler, MU

Andrews, NC

机构：

[1] Harvard Univ, Sch Med, Childrens Hosp, Boston, MA 02115 USA

[2] Childrens Hosp, Howard Hughes Med Inst, Boston, MA 02115 USA

[3] Heidelberg Univ, D-69120 Heidelberg, Germany

[4] European Mol Biol Lab, D-69117 Heidelberg, Germany

来源：

CELL | 2004年 / 117卷 / 03期

关键词：

D O I：

10.1016/S0092-8674(04)00343-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Iron is ubiquitous in the environment and in biology. The study of iron biology focuses on physiology and homeostasis-understanding how cells and organisms regulate their iron content, how diverse tissues orchestrate iron allocation, and how dysregulated iron homeostasis leads to common hematological, metabolic, and neurodegenerative diseases. This has provided novel insights into gene regulation and unveiled remarkable links to the immune system.

引用

收藏

页码：285 / 297

页数：13

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