学术探索
学术期刊
新闻热点
数据分析
智能评审

How death shapes life during development

被引：310
作者：
Baehrecke, EH [1 ]
机构：
[1] Univ Maryland, Maryland Biotechnol Inst, Ctr Biosyst Res, College Pk, MD 20742 USA
来源：
NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2002年 / 3卷 / 10期
关键词：
D O I：
10.1038/nrm931
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The formation of an adult animal from a fertilized embryo involves the production and death of cells. Surprisingly, many cells are produced during development with an ultimate fate of death, and defects in programmed cell death can result in developmental abnormalities. Recent studies indicate that cells can die by many different mechanisms, and these differences have implications for proper animal development and disorders such as cancer and autoimmunity.
引用
收藏
页码：779 / 787
页数：9
相关论文
共 118 条
  • [81] Corpse clearance defines the meaning of cell death
    Savill, J
    Fadok, V
    [J]. NATURE, 2000, 407 (6805) : 784 - 788
  • [82] DO ALL PROGRAMMED CELL DEATHS OCCUR VIA APOPTOSIS
    SCHWARTZ, LM
    SMITH, SW
    JONES, MEE
    OSBORNE, BA
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (03) : 980 - 984
  • [83] MORPHOLOGY OF VARIOUS TYPES OF CELL DEATH IN PRENATAL TISSUES
    SCHWEICHEL, JU
    MERKER, HJ
    [J]. TERATOLOGY, 1973, 7 (03) : 253 - 266
  • [84] PHYSIOLOGIC CELL NECROSES DURING EARLY DEVELOPMENT OF MUSCLES OF BACK IN EMBRYONIC MICE
    SEINSCH, W
    SCHWEICHEL, JU
    [J]. ZEITSCHRIFT FUR ANATOMIE UND ENTWICKLUNGSGESCHICHTE, 1974, 145 (01): : 101 - 112
  • [85] Biphasic intestinal development in amphibians: Embryogenesis and remodeling during metamorphosis
    Shi, YB
    IshizuyaOka, A
    [J]. CURRENT TOPICS IN DEVELOPMENTAL BIOLOGY, VOL 32, 1996, 32 : 205 - 235
  • [86] Mechanisms of caspase activation and inhibition during apoptosis
    Shi, YG
    [J]. MOLECULAR CELL, 2002, 9 (03) : 459 - 470
  • [87] FINE STRUCTURE OF MIDLINE EPITHELIUM IN DEVELOPING PALATE OF MOUSE
    SMILEY, GR
    DIXON, AD
    [J]. ANATOMICAL RECORD, 1968, 161 (03): : 293 - &
  • [88] Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
    Soengas, MS
    Capodieci, P
    Polsky, D
    Mora, J
    Esteller, M
    Opitz-Araya, X
    McCombie, R
    Herman, JG
    Gerald, WL
    Lazebnik, YA
    Cordón-Cardó, C
    Lowe, SW
    [J]. NATURE, 2001, 409 (6817) : 207 - 211
  • [89] DCP-1, a Drosophila cell death protease essential for development
    Song, ZW
    McCall, K
    Steller, H
    [J]. SCIENCE, 1997, 275 (5299) : 536 - 540
  • [90] sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein
    Srinivasula, SM
    Datta, P
    Kobayashi, M
    Wu, JW
    Fujioka, M
    Hegde, R
    Zhang, ZJ
    Mukattash, R
    Fernandes-Alnemri, T
    Shi, YG
    Jaynes, JB
    Alnemri, ES
    [J]. CURRENT BIOLOGY, 2002, 12 (02) : 125 - 130
3456789101112