Using solution-phase nanoparticles, surface-confined nanoparticle arrays and single nanoparticles as biological sensing platforms

被引:214
作者
Haes, AJ
Stuart, DA
Nie, SM
Van Duyne, RP
机构
[1] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA
[2] Emory Univ, Dept Biomed Engn, Atlanta, GA 30322 USA
[3] Emory Univ, Dept Chem, Atlanta, GA 30322 USA
[4] Georgia Inst Technol, Atlanta, GA 30332 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
nanoparticles; localized surface plasmon resonance; biosensor; streptavidin; immunoassay;
D O I
10.1023/B:JOFL.0000031817.35049.1f
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The intense colors of noble metal nanoparticles have inspired artists and fascinated scientists for hundreds of years. In this review, we describe three sensing platforms based on the tunability of the localized surface plasmon resonance (LSPR) of gold and silver nanoparticles. Specifically, the color associated with solution-phase nanoparticles, surface-confined nanoparticle arrays, and single nanoparticles will be shown to be tunable and useful as platforms for biological sensing.
引用
收藏
页码:355 / 367
页数:13
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