The potential of lipid emulsion for ocular delivery of lipophilic drugs

被引：134

作者：

Tamilvanan, S

Benita, S

机构：

[1] Hebrew Univ Jerusalem, Sch Pharm, Dept Pharmaceut, IL-91120 Jerusalem, Israel

[2] Natl Inst Pharmaceut Educ & Res, Dept Pharmaceut, Mohali, Punjab, India

来源：

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS | 2004年 / 58卷 / 02期

关键词：

emulsion; anionic; cationic; ocular bioavailability; safety; review;

D O I：

10.1016/j.ejpb.2004.03.033

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

For nearly a decade, oil-in-water lipid emulsions containing either anionic or cationic droplets have been recognized as an interesting and promising ocular topical delivery vehicle for lipophilic drugs. The aim of this review is to present the potential of lipid emulsions for ocular delivery of lipophilic drugs. The review covers an update on the state of the art of incorporating the lipophilic drugs, a brief description concerning the components and the classification of. lipid emulsions. The ocular fate following topical instillation, safety evaluation experiments and the applications of lipid emulsions are thoroughly discussed. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：357 / 368

页数：12

共 87 条

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