Moving away from death: when caspase-11 meets cofilin

被引：1

作者：

Bailly, Maryse ^{[1
]}

机构：

[1] UCL, Div Cell Biol, Inst Ophthalmol, London EC1V 9EL, England

来源：

NATURE CELL BIOLOGY | 2007年 / 9卷 / 03期

基金：

英国科研创新办公室;

关键词：

D O I：

10.1038/ncb0307-245

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 [细胞生物学]; 090102 [作物遗传育种];

摘要：

Lymphocyte migration is activated in response to inflammation and largely depends on the modulation of actin dynamics, and remodelling of the cytoskeleton, following cytokine stimulation. A novel pathway modulating inflammatory-cell migration in vivo that involves the unlikeliest of partners, the inflammatory caspase-11 and Aip1 ( an activator of cofilin-mediated actin depolymerization), has been identified.

引用

页码：245 / 246

页数：2

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