Palladium catalysed tetramolecular cascade processes incorporating allene and carbon monoxide

被引:19
作者
Grigg, R [1 ]
Brown, S [1 ]
Sridharan, V [1 ]
Uttley, MD [1 ]
机构
[1] ZENECA LTD,DEPT TECHNOL,HUDDERSFIELD HD2 1FF,W YORKSHIRE,ENGLAND
关键词
D O I
10.1016/S0040-4039(97)01062-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Chemo- and regio-specific palladium catalysed four component cascade processes, involving formation of 4 new bonds, initiated by oxidative addition of Pd(0) with aryl/heteroaryl iodides followed by sequential incorporation of CO(1atm), allene (1atm) and an S- or N-nucleophile [PhSO2-or (RNTs)(-)] occur in good to excellent yield at 50 degrees C. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码:5031 / 5034
页数:4
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