Efficient transfer hydrogenation of ketones in the presence of ruthenium N-heterocyclic carbene catalysts

被引：65

作者：

Enthaler, Stephan ^{[1
]}

Jackstell, Ralf ^{[1
]}

Hagemann, Bernhard ^{[1
]}

Junge, Kathrin ^{[1
]}

Erre, Giulia ^{[1
]}

Beller, Matthias ^{[1
]}

机构：

[1] Univ Rostock, Leibniz Inst Katalyse eV, D-18059 Rostock, Germany

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2006年 / 691卷 / 22期

关键词：

ruthenium; homogeneous catalysis; transfer hydrogenation; N-heterocyclic carbenes; ketones;

D O I：

10.1016/j.jorganchem.2006.07.013

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Novel ruthenium carbene complexes have been in situ generated and tested for the transfer hydrogenation of ketones. Applying Ru(cod)(methylallyl)2 in the presence of imidazolium salts in 2-propanol and sodium-2-propanolate as base, turnover frequencies up to 346 h(-1) have been obtained for reduction of acetophenone. A comparative study involving ruthenium carbene and ruthenium phosphine complexes demonstrated the higher activity of ruthenium carbene complexes. (c) 2006 Elsevier B.V. All rights reserved.

引用

收藏

页码：4652 / 4659

页数：8

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