Nosocomial Serratia marcescens infections associated with extrinsic contamination of a liquid nonmedicated soap

被引:76
作者
Sartor, C
Jacomo, V
Duvivier, C
Tissot-Dupont, H
Sambuc, R
Drancourt, M
机构
[1] Hop Salvator, Hyg & Epidemiol Hosp, Bacteriol Lab, Assistance Publ Hop Marseille, F-13009 Marseille, France
[2] Hop Salvator, Hyg & Epidemiol Hosp, Hop Concept, Assistance Publ Hop Marseille, F-13009 Marseille, France
[3] Assistance Hop Marseille, Comite Lutte Contre Infect Nosocomiales, Marseille, France
[4] Assistance Hop Marseille, Serv Malad Infect, Marseille, France
[5] Assistance Hop Marseille, Dept Med Informat, Marseille, France
关键词
D O I
10.1086/501743
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
OBJECTIVE: To determine the role of nonmedicated soap as a source of Serratia marcescens nosocomial infections (NIs) in hospital units with endemic S marcescens NI and to examine the mechanisms of soap colonization. SETTING: University-affiliated tertiary-care hospitals. METHODS: A prospective case-control study and an environmental investigation were performed to assess the relationship between S marcescens NIs in hospital units and S marcescens-contaminated soap. Soap-bottle use and handwashing practices were reviewed. Cultures of healthcare workers' (HCWs) hands were obtained before and after hand washing with soap. RESULTS: 5 of 7 hospital units with S marcescens NIs had soap bottles contaminated with S marcescens, compared to 1 of 14 other units (P=.006). After hand washing with an S marcescens-contaminated soap pump, HCWs' hands were 54 times more likely to be contaminated with S marcescens (P<.001). CONCLUSIONS: Extrinsic contamination of a nonmedicated liquid soap by S marcescens,ts resulted in handborne transmission of S marcescens NIs by HCWs in our setting. This finding led to the application of strict guidelines for nonmedicated soap use and to the reinforcement of alcoholic hand disinfection.
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页码:196 / 199
页数:4
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