The SWISS-MODEL repository: new features and functionalities

被引:102
作者
Kopp, Juergen
Schwede, Torsten [1 ]
机构
[1] Univ Basel, Biozentrum, Basel, Switzerland
[2] Swiss Inst Bioinformat, Basel, Switzerland
关键词
D O I
10.1093/nar/gkj056
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
TheSWISS-MODEL Repository is a database of annotated 3D protein structure models generated by the SWISS-MODEL homology-modelling pipeline. As of September 2005, the repository contained 675000 models for 604000 different protein sequences of the UniProt database. Regular updates ensure that the content of the repository reflects the current state of sequence and structure databases, integrating new or modified target sequences, and making use of new template structures. Each Repository entry consists of one or more 3D models accompanied by detailed information about the target protein and the model building process: functional annotation, a detailed template selection log, target-template alignment, summary of the model building and model quality assessment. The SWISS-MODEL Repository is freely accessible at http://swissmodel.expasy.org/repository/.
引用
收藏
页码:D315 / D318
页数:4
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