Cycloaddition reactions for the synthesis of piperidine and indolizidine alkaloids

被引：31

作者：

Holmes, AB

Bourdin, B

Collins, I

Davison, EC

Rudge, AJ

Stork, TC

Warner, JA

机构：

[1] University Chemical Laboratory, Cambridge CB2 1EW, Lensfield Road

来源：

PURE AND APPLIED CHEMISTRY | 1997年 / 69卷 / 03期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1351/pac199769030531

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The intramolecular nitrone dipolar cycloaddition of N-alkenylnitrone has been utilised in approaches to the synthesis of a family of indolizidines such as castanospermine and a tethered swainsonine analogue. Examples of a tandem hydroxylamino-alkyne cyclisation/dipolar trapping experiment in the synthesis of (+/-)-adaline and (+/-)-euphococcinine are outlined.

引用

页码：531 / 536

页数：6

共 16 条

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