Schistosomiasis of the spinal cord:: analysis of 80 cases

被引:34
作者
Peregrino, AJP
Puglia, PMK
Nóbrega, JPS
Livramento, JA
Marques-Dias, MJ
Scaff, M
机构
[1] Univ Sao Paulo, Fac Med, Hosp Clin, Div Neurol, BR-05508 Sao Paulo, Brazil
[2] FMUSP, HC, Inst Crianca, Unidade Neurol, Sao Paulo, Brazil
关键词
myelitis; myeloradiculitis; Schistosoma mansoni;
D O I
10.1590/S0004-282X2002000400016
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
To outline through cinical-laboratorial analysis a profile of schistosomiasis of the spinal cord (SSC) that contributes to the diagnosis and treatment of this disease. 80 patients were studied (59 prospectively), and epidemiological, clinical,laboratorial, treatment and outcome data extracted. In 79 patients the diagnosis was presumptive and obeyed rigorous criteria. There was a predominance of male sex (68.7%), age group from 21 to 40 years (63.7%), Northeasterners (85%), building construction workers (31.2%), previous abdominal effort (57.5%), subacute beginning (61.2%), myeloradiculitis form and lesion in conus and cauda equina (72.5%). Cerebral spinal fluid showed lymphomononuclear pleocytosis and protein increase in 100% of the cases as well as gamma globulin in 76.5%, positiveness of immunofluorescence reaction and/or ELISA for schistosomiasis in 100% of the cases with average titles of 1/16 and 61 u/dl, respectively. Corticosteroids and antischistosomal drugs were given to all patients with a satisfactory outcome in 80% of the cases. We emphasize the importance of a precocious treatment to avoid irreversible deficits such as paraplegia or sexual impotence.
引用
收藏
页码:603 / 608
页数:6
相关论文
共 42 条
[11]   THE VALUE OF AN ENZYME-LINKED-IMMUNOSORBENT-ASSAY FOR THE DIAGNOSIS OF SCHISTOSOMIASIS-MANSONI MYELORADICULOPATHY [J].
FERRARI, TCA ;
MOREIRA, PRR ;
OLIVEIRA, RC ;
FERRARI, MLA ;
GAZZINELLI, G ;
CUNHA, AS .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1995, 89 (05) :496-500
[12]  
GALHARDO I, 1974, NEUROBIOLOGIA, V37, P71
[13]  
GALVAO ACR, 1983, THESIS U SAO PAULO S
[14]   SPINAL-CORD SCHISTOSOMIASIS - A CLINICAL, LABORATORY AND RADIOLOGICAL STUDY, WITH A NOTE ON THERAPEUTIC ASPECTS [J].
HARIBHAI, HC ;
BHIGJEE, AI ;
BILL, PLA ;
PAMMENTER, MD ;
MODI, G ;
HOFFMANN, M ;
KELBE, C ;
BECKER, P .
BRAIN, 1991, 114 :709-726
[15]  
JOUBERT J, 1990, S AFR MED J, V77, P297
[16]   SCHISTOSOMIASIS OF SPINAL-CORD [J].
LECHTENBERG, R ;
VAIDA, GA .
NEUROLOGY, 1977, 27 (01) :55-59
[17]   A 40-year-old woman with the rapid onset of flaccid paraplegia - Chronic Schistosoma mansoni infection, with involvement of the large intestine and spinal cord. [J].
Liu, LX ;
Compton, CC ;
Seltzer, S ;
Jenkins, TD ;
Ueki, K ;
Cao, HY .
NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (06) :382-389
[18]  
LIVRAMENTO J A, 1986, Arquivos de Neuro-Psiquiatria, V44, P351
[19]  
Livramento J A, 1985, Arq Neuropsiquiatr, V43, P372
[20]  
LOCKE S, 1985, NEW ENGL J MED, V312, P1376, DOI 10.1056/NEJM198505233122108