Global systems biology, personalized medicine and molecular epidemiology

被引：283

作者：

Nicholson, Jeremy K. ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Fac Med, Dept Biomol Med, London, England

来源：

MOLECULAR SYSTEMS BIOLOGY | 2006年 / 2卷 / 1期

关键词：

D O I：

10.1038/msb4100095

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页数：6

共 28 条

[1] Antibiotic treatment partially protects against type 1 diabetes in the Bio-Breeding diabetes-prone rat. Is the gut flora involved in the development of type 1 diabetes? [J].

Brugman, S. ;

Klatter, F. A. ;

Visser, J. T. J. ;

Wildeboer-Veloo, A. C. M. ;

Harmsen, H. J. M. ;

Rozing, J. ;

Bos, N. A. .

DIABETOLOGIA, 2006, 49 (09) :2105-2108

[2] The application of molecular genetic approaches to the study of human evolution [J].

Cavalli-Sforza, LL ;

Feldman, MW .

NATURE GENETICS, 2003, 33 :266-275

[3] Pharmaco-metabonomic phenotyping and personalized drug treatment [J].

Clayton, TA ;

Lindon, JC ;

Cloarec, O ;

Antti, H ;

Charuel, C ;

Hanton, G ;

Provost, JP ;

Le Net, JL ;

Baker, D ;

Walley, RJ ;

Everett, JR ;

Nicholson, JK .

NATURE, 2006, 440 (7087) :1073-1077

[4] Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice [J].

Dumas, Marc-Emmanuel ;

Barton, Richard H. ;

Toye, Ayo ;

Cloarec, Olivier ;

Blancher, Christine ;

Rothwell, Alice ;

Fearnside, Jane ;

Tatoud, Roger ;

Blanc, Veronique ;

Lindon, John C. ;

Mitchell, Steve C. ;

Holmes, Elaine ;

McCarthy, Mark I. ;

Scott, James ;

Gauguier, Dominique ;

Nicholson, Jeremy K. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (33) :12511-12516

[5] Assessment of analytical reproducibility of 1H NMR spectroscopy based metabonomics for large-scale epidemiological research:: the INTERMAP study [J].

Dumas, ME ;

Maibaum, EC ;

Teague, C ;

Ueshima, H ;

Zhou, BF ;

Lindon, JC ;

Nicholson, JK ;

Stamler, J ;

Elliott, P ;

Chan, Q ;

Holmes, E .

ANALYTICAL CHEMISTRY, 2006, 78 (07) :2199-2208

[6] CYP3A genetics in drug metabolism [J].

Eichelbaum, M ;

Burk, O .

NATURE MEDICINE, 2001, 7 (03) :285-287

[7] An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences:: application to the C57BL10J and Alpk:ApfCD mouse [J].

Gavaghan, CL ;

Holmes, E ;

Lenz, E ;

Wilson, ID ;

Nicholson, JK .

FEBS LETTERS, 2000, 484 (03) :169-174

[8] Variation in gut microbiota strongly influences individual rodent phenotypes [J].

Holmes, E ;

Nicholson, J .

TOXICOLOGICAL SCIENCES, 2005, 87 (01) :1-2

[9] Infectious history [J].

Lederberg, J .

SCIENCE, 2000, 288 (5464) :287-293

[10] Transgenomic metabolic interactions in a mouse disease model:: Interactions of Trichinella spiralis infection with dietary Lactobacillus paracasei supplementation [J].

Martin, Francois-Pierre J. ;

Verdu, Elena F. ;

Wang, Yulan ;

Dumas, Marc-Emmanuel ;

Yap, Ivan K. S. ;

Cloarec, Olivier ;

Bergonzelli, Gabriela E. ;

Corthesy-Theulaz, Irene ;

Kochhar, Sunil ;

Holmes, Elaine ;

Lindon, John C. ;

Collins, Stephen M. ;

Nicholson, Jeremy K. .

JOURNAL OF PROTEOME RESEARCH, 2006, 5 (09) :2185-2193

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