Natriuretic peptides in heart failure: should therapy be guided by BNP levels?

被引：62

作者：

O'Donoghue, Michelle ^{[1
,2
]}

Braunwald, Eugene ^{[1
,2
]}

机构：

[1] Harvard Univ, TIMI Study Grp, Div Cardiovasc, Brigham & Womens Hosp,Med Sch, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Dept Med, Boston, MA 02115 USA

来源：

NATURE REVIEWS CARDIOLOGY | 2010年 / 7卷 / 01期

关键词：

LEFT-VENTRICULAR DYSFUNCTION; MEDICINE PRACTICE GUIDELINES; TRIAL VAL-HEFT; CARDIAC RESYNCHRONIZATION; CLINICAL UTILIZATION; NATIONAL-ACADEMY; BRAIN; IMPACT; CARVEDILOL; MORTALITY;

D O I：

10.1038/nrcardio.2009.197

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart failure (HF) is a leading cause of morbidity and mortality worldwide. Testing for natriuretic peptide markers, such as B-type natriuretic peptide (BNP) or N-terminal proBNP (NT-proBNP), has emerged as an important tool for the diagnosis and risk stratification of patients with HF. However, questions remain regarding the potential role for natriuretic peptides to guide therapy in patients with HF. In this Review, we address the underlying assumptions and the existing evidence supporting a natriuretic-peptide-guided approach to the outpatient management of HF.

引用

页码：13 / 20

页数：8

共 47 条

[1] Use of Aldosterone Antagonists in Heart Failure [J].

Albert, Nancy M. ;

Yancy, Clyde W. ;

Liang, Li ;

Zhao, Xin ;

Hernandez, Adrian F. ;

Peterson, Eric D. ;

Cannon, Christopher P. ;

Fonarow, Gregg C. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2009, 302 (15) :1658-1665

[2] Changes in brain natriuretic peptide and norepinephrine over time and mortality and morbidity in the Valsartan Heart Failure Trial (Val-HeFT) [J].

Anand, IS ;

Fisher, LD ;

Chiang, YT ;

Latini, R ;

Masson, S ;

Maggioni, AP ;

Glazer, RD ;

Tognoni, G ;

Cohn, JN .

CIRCULATION, 2003, 107 (09) :1278-1283

[3] ACC/AHA clinical performance measures for adults with chronic heart failure [J].

不详 .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 46 (06) :1144-1178

[4] Renal function, congestive heart failure, and amino-terminal pro-brain natriuretic peptide measurement - Results from the ProBNP Investigation of Dyspnea in the Emergency Department (PRIDE) study [J].

Anwaruddin, S ;

Lloyd-Jones, DM ;

Baggish, A ;

Chen, A ;

Krauser, D ;

Tung, R ;

Chae, C ;

Januzzi, JL .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 47 (01) :91-97

[5] N-terminal-pro-brain natriuretic peptide predicts outcome after hospital discharge in heart failure patients [J].

Bettencourt, P ;

Azevedo, A ;

Pimenta, J ;

Frioes, F ;

Ferreira, S ;

Ferreira, A .

CIRCULATION, 2004, 110 (15) :2168-2174

[6] HEART AS ENDOCRINE ORGAN [J].

BRAUNWALD, E ;

CHIDSEY, CA ;

HARRISON, DC .

AMERICAN JOURNAL OF MEDICINE, 1964, 36 (01) :1-&

[7] The effect of cardiac resynchronization on morbidity and mortality in heart failure [J].

Cleland, JGF ;

Daubert, J ;

Erdmann, E ;

Freemantle, N ;

Gras, D ;

Kappenberger, L ;

Tavazzi, L ;

Cleland, JGF ;

Daubert, JC ;

Erdmann, E ;

Gras, D ;

Kappenberger, L ;

Klein, W ;

Tavazzi, L ;

Poole-Wilson, PA ;

Rydén, L ;

Wedel, H ;

Wellens, HJJ ;

Uretsky, B ;

Thygesen, K ;

Böcker, D ;

Marijianowski, MMH ;

Freemantle, N ;

Calvert, MJ ;

Christ, G ;

Fruhwald, F ;

Hofmann, R ;

Krypta, A ;

Leisch, F ;

Pacher, R ;

Rauscha, F ;

Tavernier, R ;

Thomsen, PEB ;

Boesgaard, S ;

Eiskjær, H ;

Esperen, GT ;

Haarbo, J ;

Hagemann, A ;

Korup, E ;

Moller, M ;

Mortensen, P ;

Sogaard, P ;

Vesterlund, T ;

Huikuri, H ;

Niemelä, KI ;

Toivonen, L ;

Bauer, F ;

Cohen-Solal, A ;

Crocq, C ;

Djiane, P .

NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (15) :1539-1549

[8] Predicting the long-term effects of cardiac resynchronization therapy on mortality from baseline variables and the early response - A report from the CARE-HF (Cardiac Resynchronization in Heart Failure) trial [J].

Cleland, John ;

Freemantle, Nick ;

Ghio, Stefano ;

Fruhwald, Friedrich ;

Shankar, Aparna ;

Marijanowski, Monique ;

Verboven, Yves ;

Tavazzi, Luigi .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 52 (06) :438-445

[9] Introduction of metoprolol increases plasma B-type cardiac natriuretic peptides in mild, stable heart failure [J].

Davis, ME ;

Richards, AM ;

Nicholls, G ;

Yandle, TG ;

Frampton, CM ;

Troughton, RW .

CIRCULATION, 2006, 113 (07) :977-985

[10] A RAPID AND POTENT NATRIURETIC RESPONSE TO INTRAVENOUS-INJECTION OF ATRIAL MYOCARDIAL EXTRACT IN RATS [J].

DEBOLD, AJ ;

BORENSTEIN, HB ;

VERESS, AT ;

SONNENBERG, H .

LIFE SCIENCES, 1981, 28 (01) :89-94

← 1 2 3 4 5 →