Study of a molecular imprinting polymer coated BAW bio-mimic sensor and its application to the determination of caffeine in human serum and urine

被引：72

作者：

Liang, CD ^{[1
]}

Peng, H ^{[1
]}

Bao, XY ^{[1
]}

Nie, LH ^{[1
]}

Yao, SZ ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, Changsha 410082, Peoples R China

来源：

ANALYST | 1999年 / 124卷 / 12期

关键词：

D O I：

10.1039/a905112k

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A bio-mimic bulk acoustic wave (BAW) sensor was fabricated by coating the caffeine (CAF) template molecular imprinting polymer (MIP). This sensor exhibited high selectivity and a sensitive mass response to CAF. The response range of the sensor was between 5.0 x 10(-9) and 1.0 x 10(-4) M with a detection limit of 5.0 x 10(-9) M at pH 8.0. Recoveries were 96.1-105.6%. Influencing factors were investigated in detail and optimized. When employed to detect real samples, the proposed method proved to be a convenient method with the advantages of high sensitivity, good selectivity and ease of handling.

引用

页码：1781 / 1785

页数：5

共 28 条

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