Sequential biocatalytic resolution of (+/-)-trans-cyclohexane-1,2-diamine. Chemoenzymatic synthesis of an optically active polyamine

被引：33

作者：

Alfonso, I ^{[1
]}

Astorga, C ^{[1
]}

Rebolledo, F ^{[1
]}

Gotor, V ^{[1
]}

机构：

[1] UNIV OVIEDO, DEPT QUIM ORGAN & INORGAN, OVIEDO 33071, SPAIN

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 21期

关键词：

D O I：

10.1039/cc9960002471

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Candida antarctica lipase-catalysed double monoaminolysis of dimethyl malonate by (+/-)-trans-cyclohexane-1,2-diamine allows the sequential resolution of the latter compound, affording an enantiopure bis(amidoester), (R,R)-3, which is subsequently transformed into an optically active polyamine, (R,R)-9.

引用

页码：2471 / 2472

页数：2

共 22 条

[1] [Anonymous], ADV POLYAMINE RES
[2] [Anonymous], ADV POLYAMINE RES
[3] ENZYMATIC AMINOLYSIS OF NONACTIVATED DIESTERS WITH DIAMINES
ASTORGA, C
REBOLLEDO, F
GOTOR, V
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1994, (07): : 829 - 832
[4] BELOKON N, 1996, TETRAHEDRON-ASYMMETR, V7, P851
[5] REGIOSELECTIVITY AND ENANTIOSELECTIVITY OF THE CANDIDA-ANTARCTICA LIPASE-CATALYZED AMIDATIONS OF CBZ-L-GLUTAMIC AND CBZ-D-GLUTAMIC ACID DIESTERS
CHAMORRO, C
GONZALEZMUNIZ, R
CONDE, S
[J]. TETRAHEDRON-ASYMMETRY, 1995, 6 (09) : 2343 - 2352
[6] GENERAL-ASPECTS AND OPTIMIZATION OF ENANTIOSELECTIVE BIOCATALYSIS IN ORGANIC-SOLVENTS - THE USE OF LIPASES
CHEN, CS
SIH, CJ
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1989, 28 (06): : 695 - 707
[7] QUANTITATIVE-ANALYSES OF BIOCHEMICAL KINETIC RESOLUTIONS OF ENANTIOMERS
CHEN, CS
FUJIMOTO, Y
GIRDAUKAS, G
SIH, CJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1982, 104 (25) : 7294 - 7299
[8] LIPASE-CATALYZED AMINOLYSIS AND AMMONOLYSIS OF BETA-KETOESTERS - SYNTHESIS OF OPTICALLY-ACTIVE BETA-KETOAMIDES
GARCIA, MJ
REBOLLEDO, F
GOTOR, V
[J]. TETRAHEDRON, 1994, 50 (23) : 6935 - 6940
[9] GARCIA MJ, 1993, TETRAHEDRON-ASYMMETR, V4, P2199
[10] GOLDENBURG SH, 1990, BIOL CHEM POLYAMINES

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