Mandibular reconstruction: A clinical and radiographic animal study on the use of autogenous scaffolds and platelet-rich plasma

被引：108

作者：

Fennis, JPM

Stoelinga, PJW

Jansen, JA

机构：

[1] Univ Nijmegen, Med Ctr, Dept Oral & Maxillofacial Surg, Nijmegen, Netherlands

[2] Univ Nijmegen, Med Ctr, Dept Biomat, Nijmegen, Netherlands

来源：

INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 2002年 / 31卷 / 03期

关键词：

mandibular reconstruction; platelet-rich plasma (PRP); experimental animals;

D O I：

10.1054/ijom.2002.0151

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

This paper reports on an experimental animal study evaluating a method of mandibular reconstruction. After a successful pilot study, 28 goats underwent a continuity resection of the mandibular angle. Primary reconstruction was carried out using specially designed osteosynthesis plates and screws. The defect was bridged by the original cortical scaffold, filled with an autogenous bone graft from the iliac crest. To accelerate bone healing, platelet-rich plasma (PRP) was mixed with the particulate bone graft in 14 goats. All goats had uneventful healing. The osteosynthesis plates and screws withstood immediate loading for periods varying from 3 weeks to 3 months. The use of PRP appeared to enhance bone healing considerably.

引用

收藏

页码：281 / 286

页数：6

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