Aldehyde-Amine Chemistry Enables Modulated Biosealants with Tissue-Specific Adhesion

被引：106

作者：

Artzi, Natalie ^{[1
,2
]}

Shazly, Tarek ^{[1
]}

Baker, Aaron B. ^{[1
,2
]}

Bon, Adriana ^{[3
]}

Edelman, Elazer R. ^{[1
,2
]}

机构：

[1] MIT, Harvard MIT Div Hlth Sci & Technol, Cambridge, MA 02139 USA

[2] Harvard Univ, Brigham & Womens Hosp, Sch Med,Dept Med, Div Cardiovasc, Boston, MA 02115 USA

[3] Univ Ramon Llull, Inst Quim Sarria, Barcelona 08017, Spain

来源：

ADVANCED MATERIALS | 2009年 / 21卷 / 32-33期

基金：

美国国家卫生研究院;

关键词：

FIBRIN GLUE; CYANOACRYLATE; ANASTOMOSIS; SEALANT;

D O I：

10.1002/adma.200900340

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

The interfacial regions between PEG: dextran-based adhesive sealant and excised rat heart, lung, liver, and duodenum tissues exhibit three distinct domains; target tissue (red and blue), bulk material (green), and an adhesive regime interposed between the two. The variation in adhesive regime morphology when applied to different tissues provides a rational approach for the engineering of application-specific surgical sealants.

引用

页码：3399 / +

页数：6

共 23 条

[1]

Creation of a uniform pleural defect model for the study of lung sealants [J].

Araki, Masato ;

Tao, Hiroyuki ;

Sato, Toshihiko ;

Nakajima, Naoki ;

Sugai, Hajime ;

Hyon, Suong-Hyu ;

Nagayasu, Takeshi ;

Nakamura, Tatsuo .

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2007, 134 (01) :145-151

[2]

Characterization of Star Adhesive Sealants Based On PEG/Dextran Hydrogels [J].

Artzi, Natalie ;

Shazly, Tarek ;

Crespo, Cristina ;

Ramos, Adriana Bon ;

Chenault, H. Keith ;

Edelman, Elazer R. .

MACROMOLECULAR BIOSCIENCE, 2009, 9 (08) :754-765

[3]

Polysaccharide-based tissue adhesives for sealing corneal incisions [J].

Bhatia, Sujata K. ;

Arthur, Samuel D. ;

Chenault, H. Keith ;

Figuly, Garret D. ;

Kodokian, George K. .

CURRENT EYE RESEARCH, 2007, 32 (12) :1045-1050

[4]

Interactions of polysaccharide-based tissue adhesives with clinically relevant fibroblast and macrophage cell lines [J].

Bhatia, Sujata K. ;

Arthur, Samuel D. ;

Chenault, H. Keith ;

Kodokian, George K. .

BIOTECHNOLOGY LETTERS, 2007, 29 (11) :1645-1649

[5]

CLAYDEN J, 2001, ORGANIC CHEM, pCH14

[6]

No detrimental effects of repeated laparotomies on early healing of experimental intestinal anastomoses [J].

de Hingh, IHJT ;

van Goor, H ;

de Man, BM ;

Lomme, RMLM ;

Bleichrodt, RP ;

Hendriks, T .

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 2005, 20 (06) :534-541

[7]

EKELUND A, 1991, INT ORTHOP, V15, P331

[8]

HIGH RESOLUTION IN SITU ZYMOGRAPHY REVEALS MATRIX METALLOPROTEINASE ACTIVITY AT GLUTAMATERGIC SYNAPSES [J].

Gawlak, M. ;

Gorkiewicz, T. ;

Gorlewicz, A. ;

Konopacki, F. A. ;

Kaczmarek, L. ;

Wilczynski, G. M. .

NEUROSCIENCE, 2009, 158 (01) :167-176

[9]

SUTURELESS COLON ANASTOMOSIS WITH FIBRIN GLUE IN THE RAT [J].

HAUKIPURO, KA ;

HULKKO, OA ;

ALAVAIKKO, MJ ;

LAITINEN, ST .

DISEASES OF THE COLON & RECTUM, 1988, 31 (08) :601-604

[10]

The seating effect of fibrin glue against alveolar air leakage evaluated up to 48 h; comparison between different methods of application [J].

Kawamura, M ;

Gika, M ;

Izumi, Y ;

Horinouchi, H ;

Shinya, N ;

Mukai, M ;

Kobayashi, K .

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2005, 28 (01) :39-42

← 1 2 3 →