Comorbidity of depression with other medical diseases in the elderly

被引：153

作者：

Krishnan, KRR

Delong, M

Kraemer, H

Carney, R

Spiegel, D

Gordon, C

McDonald, W

Dew, MA

Alexopoulos, G

Buckwalter, K

Cohen, PD

Evans, D

Kaufmann, PG

Olin, J

Otey, E

Wainscott, C

机构：

[1] Duke Univ, Med Ctr, Dept Psychiat & Behav Sci, Durham, NC 27710 USA

[2] Emory Univ, Sch Med, Atlanta, GA USA

[3] Stanford Univ, Sch Med, Stanford, CA 94305 USA

[4] Washington Univ, Sch Med, St Louis, MO USA

[5] NIMH, Bethesda, MD 20892 USA

[6] Univ Pittsburgh, Western Psychiat Inst & Clin, Pittsburgh, PA 15213 USA

[7] Cornell Univ, Ithaca, NY USA

[8] Univ Iowa, Iowa City, IA USA

[9] Parkinsons Dis Fdn, New York, NY USA

[10] Univ Penn, Philadelphia, PA 19104 USA

[11] NHLBI, Bethesda, MD 20892 USA

[12] Natl Mental Hlth Assoc Georgia, Atlanta, GA USA

来源：

BIOLOGICAL PSYCHIATRY | 2002年 / 52卷 / 06期

关键词：

age; depression; medical; cardiac; cancer; HIV;

D O I：

10.1016/S0006-3223(02)01472-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A major factor in the context of evaluating depression in the elderly is the role of medical problems. With aging there is a rapid increase in the prevalence of a number of medical disorders, including cancer, heart disease, Parkinson's disease, Alzheimer's disease, stroke, and arthritis. In this article, we hope to bring clarity to the definition of comorbidity and then discuss a number of medical disorders as they relate to depression. We evaluate medical comorbidity as a risk factor for depression as well as the converse, that is, depression as a risk factor for medical illness. Most of the disorders that we focus on occur in the elderly, with the exception of HIV infection. This review focuses exclusively on unipolar disorder. The review summarizes the current state of the art and also makes recommendations for future directions.

引用

页码：559 / 588

页数：30

共 332 条

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