Overlapping and specific patterns of GDNF, c-ret and GFRα mRNA expression in the developing chicken retina

被引：18

作者：

Karlsson, M ^{[1
]}

Lindqvist, N ^{[1
]}

Mayordomo, R ^{[1
]}

Hallböök, F ^{[1
]}

机构：

[1] Univ Uppsala, Dept Neurosci, S-75123 Uppsala, Sweden

来源：

MECHANISMS OF DEVELOPMENT | 2002年 / 114卷 / 1-2期

关键词：

amacrine cells; avian; embryonic; ganglion cells; horizontal cells; in situ hybridisation; kinase receptor; mRNA; neurotrophic factor; photoreceptors;

D O I：

10.1016/S0925-4773(02)00045-X

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

GDNF and the GDNF receptors, c-Ret, GFRalpha1 and 2 mRNA is expressed in the developing chicken retina. GDNF labelling was mainly found in embryonic day 4-5 retina but weak labelling could also be found over scattered retinal cells at later stages, c-ret labelling was found over ganglion cells, amacrine and horizontal cells; the preferred GDNF receptor (GFRalpha1) over amacrine and horizontal cells; and the less preferred GDNF receptor (GFRalpha2) over ganglion cells, amacrine cells and photoreceptors. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.

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页码：161 / 165

页数：5

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