Overlapping and specific patterns of GDNF, c-ret and GFRα mRNA expression in the developing chicken retina

被引:18
作者
Karlsson, M [1 ]
Lindqvist, N [1 ]
Mayordomo, R [1 ]
Hallböök, F [1 ]
机构
[1] Univ Uppsala, Dept Neurosci, S-75123 Uppsala, Sweden
关键词
amacrine cells; avian; embryonic; ganglion cells; horizontal cells; in situ hybridisation; kinase receptor; mRNA; neurotrophic factor; photoreceptors;
D O I
10.1016/S0925-4773(02)00045-X
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
GDNF and the GDNF receptors, c-Ret, GFRalpha1 and 2 mRNA is expressed in the developing chicken retina. GDNF labelling was mainly found in embryonic day 4-5 retina but weak labelling could also be found over scattered retinal cells at later stages, c-ret labelling was found over ganglion cells, amacrine and horizontal cells; the preferred GDNF receptor (GFRalpha1) over amacrine and horizontal cells; and the less preferred GDNF receptor (GFRalpha2) over ganglion cells, amacrine cells and photoreceptors. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:161 / 165
页数:5
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