Mytilus edulis histone gene clusters containing only H1 genes

被引:14
作者
Drabent, B
Kim, JS
Albig, W
Prats, E
Cornudella, L
Doenecke, D
机构
[1] Univ Gottingen, Dept Mol Biol, Inst Biochem & Mol Cell Biol, D-37073 Gottingen, Germany
[2] CSIC, Ctr Invest & Desarrollo, Dept Mol & Cell Biol, E-08034 Barcelona, Spain
关键词
Mytilus edulis; H1 histone genes; gene organization; nucleotide sequence;
D O I
10.1007/PL00006585
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We isolated five different phage clones containing histone gene clusters with up to five H1 genes per phage clone from a Mytilus edulis genomic library. Among these Ill genes, nine gene types coding for five different H1 proteins have been identified. All H1 histone genes were located on repetitive restriction fragments with only slightly different sizes. The H1 coding regions show highly related sequences, suggesting that the multitude of H1 genes has evolved by gene duplication events. Core histone genes could not be found on these five Mytilus edulis genome fragments.
引用
收藏
页码:645 / 655
页数:11
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