The application of histo-cytopathological biomarkers in marine pollution monitoring: a review

被引：353

作者：

Au, DWT ^{[1
]}

机构：

[1] City Univ Hong Kong, Dept Biol & Chem, Ctr Coastal Pollut & Conservat, Kowloon, Hong Kong, Peoples R China

来源：

MARINE POLLUTION BULLETIN | 2004年 / 48卷 / 9-10期

关键词：

biomarkers; fish diseases; histo-cytopathology; marine pollution; xenobiotics;

D O I：

10.1016/j.marpolbul.2004.02.032

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

During the past two decades, a variety of histopathological alterations in fish and bivalves have been developed and used as biomarkers in pollution monitoring. Some of these have been successfully adopted in major national monitoring programmes, while others. although show promise, are still in the experimental stage. This paper critically reviews the scientific basis, cause and effect relationship, reliability, advantages and limitations of 14 histo-cytopathological biomarkers. The usefulness and practical application of each biomarker have been evaluated against a number of objective criteria including: ecological relevance, sensitivity, specificity, dose-response relationship, confounding factors, technical difficulties and cost-effectiveness. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：817 / 834

页数：18

共 179 条

[31] Seasonal variation of peroxisomal enzyme activities and peroxisomal structure in mussels Mytilus galloprovincialis and its relationship with the lipid content [J].