Endoscopic treatments for portal hypertension

被引:156
作者
de Franchis, R [1 ]
Primignani, M [1 ]
机构
[1] Univ Milan, Dipartimento Med Interna, Gastroenterol & Gastrointestinal Endoscopy Serv, I-20122 Milan, Italy
关键词
variceal bleeding; endoscopic treatment; meta-analysis;
D O I
10.1055/s-2007-1007131
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Endoscopic treatments for bleeding gastroesophageal varices include injection sclerotherapy, variceal obturation with tissue adhesives, and variceal rubber band ligation. Acute injection sclerotherapy remains a quick and simple technique for the control of active bleeding from esophageal varices. Although few trials have been published so far; some evidence suggests that the early administration of vasoactive drugs (somatostatin, octreotide, or terlipressin) is safe and may increase the efficacy of endoscopic treatments, Banding ligation is the optimal endoscopic treatment for the prevention of rebleeding from esophageal varices, The use of tissue adhesives and thrombin as injectates to treat bleeding fundal gastric varices and esophageal varices not responding to vasoactive drugs or sclerotherapy is promising but needs further assessment by means of randomized controlled trials. As of toda): endoscopic treatments are not recommended for the primary prophylaxis of variceal bleeding.
引用
收藏
页码:439 / 455
页数:17
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