In vitro activities of investigational triazoles against Fusarium species:: Effects of inoculum size and incubation time on broth microdilution susceptibility test results

被引:51
作者
Paphitou, NI [1 ]
Ostrosky-Zeichner, L [1 ]
Paetznick, VL [1 ]
Rodriguez, JR [1 ]
Chen, EN [1 ]
Rex, JH [1 ]
机构
[1] Univ Texas, Sch Med, Lab Mycol Res, Ctr Study Emerging & Reemerging Pathogens,Div Inf, Houston, TX 77030 USA
关键词
D O I
10.1128/AAC.46.10.3298-3300.2002
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We studied the effects of inoculum size and incubation time on the susceptibility testing results for various antifungal agents against 22 Fusarium isolates by the NCCLS microdilution method. Increased inoculum size and extended incubation time resulted in elevated MICs. Posaconazole and voriconazole exhibited promising antifungal activities.
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收藏
页码:3298 / 3300
页数:3
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