Synthesis and self-assembly of organoclay-wrapped biomolecules

被引:117
作者
Patil, AJ [1 ]
Muthusamy, E [1 ]
Mann, S [1 ]
机构
[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England
基金
英国工程与自然科学研究理事会;
关键词
biological activity; nanoparticles; organic-inorganic hybrid composites; self-assembly;
D O I
10.1002/anie.200453868
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Gift wrapped: Biomolecules can be enveloped within an ultrathin shell of an aminopropyl-functionalized magnesium (organo)phyllosilicate to produce aqueous dispersions of discrete protein-inorganic nanoparticles. Similar procedures but with organoclay oligomers that have pendent long-chain hydrophobic moieties result in self-assembly of the protein-inorganic nanoparticles into higher-order superstructures (see picture).
引用
收藏
页码:4928 / 4933
页数:6
相关论文
共 20 条
[1]   REVERSIBLE DENATURATION OF SPERM WHALE MYOGLOBIN .I. DEPENDENCE ON TEMPERATURE PH AND COMPOSITION [J].
ACAMPORA, G ;
HERMANS, J .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1967, 89 (07) :1543-&
[2]   Using the glucose oxidase peroxidase system in enzyme kinetics [J].
Bateman, RC ;
Evans, JA .
JOURNAL OF CHEMICAL EDUCATION, 1995, 72 (12) :A240-A241
[3]   Synthesis, characterization, and reactivity of layered inorganic-organic nanocomposites based on 2:1 trioctahedral phyllosilicates [J].
Burkett, SL ;
Press, A ;
Mann, S .
CHEMISTRY OF MATERIALS, 1997, 9 (05) :1071-&
[4]   Enzyme multilayers on colloid particles:: Assembly, stability, and enzymatic activity [J].
Caruso, F ;
Schüler, C .
LANGMUIR, 2000, 16 (24) :9595-9603
[5]   ENCAPSULATION OF PROTEINS IN TRANSPARENT POROUS SILICATE-GLASSES PREPARED BY THE SOL-GEL METHOD [J].
ELLERBY, LM ;
NISHIDA, CR ;
NISHIDA, F ;
YAMANAKA, SA ;
DUNN, B ;
VALENTINE, JS ;
ZINK, JI .
SCIENCE, 1992, 255 (5048) :1113-1115
[6]   Colloids, helices, and patterned films made from heme proteins and manganese oxide [J].
Gao, QM ;
Suib, SL ;
Rusling, JF .
CHEMICAL COMMUNICATIONS, 2002, (19) :2254-2255
[7]   Bioencapsulation within synthetic polymers (Part 1): sol-gel encapsulated biologicals [J].
Gill, I ;
Ballesteros, A .
TRENDS IN BIOTECHNOLOGY, 2000, 18 (07) :282-296
[8]   Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials [J].
Hartgerink, JD ;
Beniash, E ;
Stupp, SI .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (08) :5133-5138
[9]   Novel peptide-based biomaterial scaffolds for tissue engineering [J].
Holmes, TC .
TRENDS IN BIOTECHNOLOGY, 2002, 20 (01) :16-21
[10]   Wrapping and inclusion of organic molecules with ultrathin, amorphous metal oxide films [J].
Ichinose, I ;
Kunitake, T .
CHEMICAL RECORD, 2002, 2 (05) :339-351