Antitumour activities of levans produced by Zymomonas mobilis strains

被引：69

作者：

Calazans, GMT ^{[1
]}

Lopes, CE ^{[1
]}

Lima, RMOC ^{[1
]}

deFranca, FP ^{[1
]}

机构：

[1] FED UNIV RIO DE JANEIRO,CTR TECNOL,ESCOLA QUIM,DEPT ENGN BIOQUIM,BR-21941990 RIO JANEIRO,BRAZIL

来源：

BIOTECHNOLOGY LETTERS | 1997年 / 19卷 / 01期

关键词：

Polymer; Carcinoma; Molecular Weight; Organic Chemistry; Polysaccharide;

D O I：

10.1023/A:1018350617120

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Levans produced by four Zymomonas mobilis strains showed antitumour activity against sarcoma 180 and Ehrlich carcinoma in Swiss albino mice. Levans from two strains (ZAP and CP4) had the highest effects. NMR analysis showed that the polymers were composed only of fructose units. The results suggested that the antineoplasic effect is associated to the polysaccharide molecular weight and that a particular molecular weight range may be responsible for this effect.

引用

页码：19 / 21

页数：3

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