Secular trends in hip fracture incidence and recurrence

被引:158
作者
Melton, L. J., III [1 ,3 ,5 ]
Kearns, A. E. [3 ]
Atkinson, E. J. [2 ]
Bolander, M. E. [5 ]
Achenbach, S. J. [2 ]
Huddleston, J. M. [4 ]
Therneau, T. M. [2 ]
Leibson, C. L. [1 ]
机构
[1] Mayo Clin, Div Epidemiol, Dept Hlth Sci Res, Coll Med, Rochester, MN 55905 USA
[2] Mayo Clin, Div Biostat, Dept Hlth Sci Res, Coll Med, Rochester, MN 55905 USA
[3] Mayo Clin, Div Endocrinol, Dept Internal Med, Coll Med, Rochester, MN 55905 USA
[4] Mayo Clin, Div Hosp Internal Med, Dept Internal Med, Coll Med, Rochester, MN 55905 USA
[5] Mayo Clin, Dept Orthoped Surg, Coll Med, Rochester, MN 55905 USA
基金
美国国家卫生研究院;
关键词
Aging; Hip fracture; Incidence; Population-based study; Recurrence; Secular trends; CLINICAL FRACTURES; RISK-FACTORS; MORTALITY; NECK; OSTEOPOROSIS; WOMEN; EPIDEMIOLOGY; PREVENTION; PROGRAM; 1ST;
D O I
10.1007/s00198-008-0742-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The decline in hip fracture incidence is now accompanied by a further reduction in the likelihood of a recurrent hip fracture among survivors of the first fracture. Hip fracture incidence is declining in North America, but trends in hip fracture recurrence have not been described. All hip fracture events among Olmsted County, Minnesota residents in 1980-2006 were identified. Secular trends were assessed using Poisson regression, and predictors of recurrence were evaluated with Andersen-Gill time-to-fracture regression models. Altogether, 2,752 hip fractures (median age, 83 years; 76% female) were observed, including 311 recurrences. Between 1980 and 2006, the incidence of a first-ever hip fracture declined by 1.37%/year for women (p < 0.001) and 0.06%/year for men (p = 0.917). Among 2,434 residents with a first-ever hip fracture, the cumulative incidence of a second hip fracture after 10 years was 11% in women and 6% in men with death treated as a competing risk. Age and calendar year of fracture were independently associated with hip fracture recurrence. Accounting for the reduction in first-ever hip fracture rates over time, hip fracture recurrence appeared to decline after 1997. A recent reduction in hip fracture recurrence is somewhat greater than expected from the declining incidence of hip fractures generally. Additional research is needed to determine the extent to which this can be attributed to improved patient management.
引用
收藏
页码:687 / 694
页数:8
相关论文
共 45 条
  • [21] Population trends in BMD testing, treatment, and hip and wrist fracture rates: are the hip fracture projections wrong?
    Jaglal, SB
    Weller, I
    Mamdani, M
    Hawker, G
    Kreder, H
    Jaakkimainen, L
    Adachi, JD
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2005, 20 (06) : 898 - 905
  • [22] Kalbfleisch John D, 2011, The statistical analysis of failure time data
  • [23] Excess mortality after hospitalisation for vertebral fracture
    Kanis, JA
    Oden, A
    Johnell, O
    De Laet, C
    Jonsson, B
    [J]. OSTEOPOROSIS INTERNATIONAL, 2004, 15 (02) : 108 - 112
  • [24] Nationwide decline in incidence of hip fracture
    Kannus, Pekka
    Niemi, Seppo
    Parkkari, Jari
    Palvanen, Mika
    Vuori, Ilkka
    Jarvinen, Markku
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2006, 21 (12) : 1836 - 1838
  • [25] NONPARAMETRIC-ESTIMATION FROM INCOMPLETE OBSERVATIONS
    KAPLAN, EL
    MEIER, P
    [J]. JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 1958, 53 (282) : 457 - 481
  • [26] Patients with prior fractures have an increased risk of future fractures: A summary of the literature and statistical synthesis
    Klotzbuecher, CM
    Ross, PD
    Landsman, PB
    Abbott, TA
    Berger, M
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2000, 15 (04) : 721 - 739
  • [27] Incidence of second hip fractures.: A population-based study
    Lonnroos, E.
    Kautiainen, H.
    Karppi, P.
    Hartikainen, S.
    Kiviranta, I.
    Sulkava, R.
    [J]. OSTEOPOROSIS INTERNATIONAL, 2007, 18 (09) : 1279 - 1285
  • [28] Zoledronic acid and clinical fractures and mortality after hip fracture
    Lyles, Kenneth W.
    Colon-Emeric, Cathleen S.
    Magaziner, Jay S.
    Adachi, Jonathan D.
    Pieper, Carl F.
    Mautalen, Carlos
    Hyldstrup, Lars
    Recknor, Chris
    Nordsletten, Lars
    Moore, Kathy A.
    Lavecchia, Catherine
    Zhang, Jie
    Mesenbrink, Peter
    Hodgson, Patricia K.
    Abrams, Ken
    Orloff, John J.
    Horowitz, Zebulun
    Eriksen, Erik Fink
    Boonen, Steven
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (18) : 1799 - 1809
  • [29] Displaced femoral neck fractures in the elderly: Hemiarthroplasty versus total hip arthroplasty
    Macaulay, W
    Pagnotto, MR
    Iorio, R
    Mont, MA
    Saleh, KJ
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS, 2006, 14 (05) : 287 - 293
  • [30] High-trauma fractures and low bone mineral density in older women and men
    Mackey, Dawn C.
    Lui, Li-Yung
    Cawthon, Peggy M.
    Bauer, Douglas C.
    Nevitt, Michael C.
    Cauley, Jane A.
    Hillier, Teresa A.
    Lewis, Cora E.
    Barrett-Connor, Elizabeth
    Cummings, Steven R.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 298 (20): : 2381 - 2388