A convenient synthesis of trifluoromethyl ethers by oxidative desulfurization-fluorination of dithio carbonates

被引：61

作者：

Kanie, K ^{[1
]}

Tanaka, Y ^{[1
]}

Suzuki, K ^{[1
]}

Kuroboshi, M ^{[1
]}

Hiyama, T ^{[1
]}

机构：

[1] Tokyo Inst Technol, Resources Utilizat Res Lab, Midori Ku, Kanagawa 2268503, Japan

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 2000年 / 73卷 / 02期

关键词：

D O I：

10.1246/bcsj.73.471

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Trifluoromethyl ethers R-OCF3 are easily synthesized from the corresponding dithiocarbonates R-OCS2Me (R = aryl or primary alkyl) by a reagent system consisting of 70% HF/pyridine and an N-halo imide. When the reaction is applied to R-OCS2Me wherein R = secondary alkyl, tertiary alkyl, or benzylic group, fluorination leading to the corresponding alkyl fluorides R-F is achieved, whereas a combination of 50% HF/pyridine and N-bromosuccinimide affords the corresponding trifluoromethyl ethers R-OCF3 (R = secondary).

引用

页码：471 / 484

页数：14

共 55 条

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