Colonization with extraintestinal pathogenic Escherichia coli among nursing home residents and its relationship to fluoroquinolone resistance

被引:19
作者
Maslow, JN
Lautenbach, E
Glaze, T
Bilker, W
Johnson, JR
机构
[1] Vet Affairs Med Ctr, Infect Dis Sect, Philadelphia, PA 19104 USA
[2] Univ Penn, Div Infect Dis, Philadelphia, PA 19104 USA
[3] Univ Penn, Ctr Clin Epidemiol & Biostat, Philadelphia, PA 19104 USA
[4] Univ Penn, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA
[5] Univ Penn, Ctr Educ & Res Therapeut, Philadelphia, PA 19104 USA
[6] Univ Minnesota, Dept Med, Minneapolis, MN 55455 USA
[7] Vet Affairs Med Ctr, Mucosal & Vaccine Res Ctr, Minneapolis, MN 55455 USA
关键词
D O I
10.1128/AAC.48.9.3618-3620.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In a cross-sectional fecal prevalence survey involving 49 residents of a Veterans Affairs nursing home, 59% of subjects were colonized with extraintestinal pathogenic Escherichia coli (ExPEC), 22% were colonized with adhesin-positive E. coli, and 51% were colonized with fluoroquinolone-resistant E. coli. Among 80 unique isolates, adhesins correlated negatively and aerobactin correlated positively with fluoroquinolone resistance.
引用
收藏
页码:3618 / 3620
页数:3
相关论文
共 15 条
[1]   DETECTION BY MOLECULAR HYBRIDIZATION OF PAP, AFA, AND SFA ADHERENCE SYSTEMS IN ESCHERICHIA-COLI STRAINS ASSOCIATED WITH URINARY AND ENTERAL INFECTIONS [J].
ARCHAMBAUD, M ;
COURCOUX, P ;
LABIGNEROUSSEL, A .
ANNALES DE L INSTITUT PASTEUR-MICROBIOLOGIE, 1988, 139 (05) :575-588
[2]   Antimicrobial resistance in isolates from inpatients and outpatients in the united states: Increasing importance of the intensive care unit [J].
Archibald, L ;
Phillips, L ;
Monnet, D ;
McGowan, JE ;
Tenover, F ;
Gaynes, R .
CLINICAL INFECTIOUS DISEASES, 1997, 24 (02) :211-215
[3]   Rapid and simple determination of the Escherichia coli phylogenetic group [J].
Clermont, O ;
Bonacorsi, S ;
Bingen, E .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2000, 66 (10) :4555-4558
[4]   Phylogenetic origin and virulence genotype in relation to resistance to fluoroquinolones and/or extended-spectrum cephalosporins and cephamycins among Escherichia coli isolates from animals and humans [J].
Johnson, JR ;
Kuskowski, MA ;
Owens, K ;
Gajewski, A ;
Winokur, PL .
JOURNAL OF INFECTIOUS DISEASES, 2003, 188 (05) :759-768
[5]   Extended virulence genotypes of Escherichia coli strains from patients with urosepsis in relation to phylogeny and host compromise [J].
Johnson, JR ;
Stell, AL .
JOURNAL OF INFECTIOUS DISEASES, 2000, 181 (01) :261-272
[6]  
KALLENIUS G, 1981, LANCET, V2, P1369
[7]   Risk factors for fluoroquinolone resistance in nosocomial Escherichia coli and Klebsiella pneumoniae infections [J].
Lautcnbach, E ;
Fishman, NO ;
Bilker, WB ;
Castiglioni, A ;
Metlay, JP ;
Edelstein, PH ;
Strom, BL .
ARCHIVES OF INTERNAL MEDICINE, 2002, 162 (21) :2469-2477
[8]   Epidemiological investigation of fluoroquinolone resistance in infections due to extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae [J].
Lautenbach, E ;
Strom, BL ;
Bilker, WB ;
Patel, JB ;
Edelstein, PH ;
Fishman, NO .
CLINICAL INFECTIOUS DISEASES, 2001, 33 (08) :1288-1294
[9]   Low-level colonization and infection with ciprofloxacin-resistant gram-negative bacilli in a skilled nursing facility [J].
Lee, YL ;
Cesario, T ;
McCauley, V ;
Flionis, L ;
Pax, A ;
Thrupp, L .
AMERICAN JOURNAL OF INFECTION CONTROL, 1998, 26 (06) :552-557
[10]   BACTERIAL ADHESINS AND HOST FACTORS - ROLE IN THE DEVELOPMENT AND OUTCOME OF ESCHERICHIA-COLI BACTEREMIA [J].
MASLOW, JN ;
MULLIGAN, ME ;
ADAMS, KS ;
JUSTIS, JC ;
ARBEIT, RD .
CLINICAL INFECTIOUS DISEASES, 1993, 17 (01) :89-97