Expeditious selective synthesis of primary rim tri-differentiated α-cyclodextrin

被引：30

作者：

Bistri, Olivia

Sinay, Pierre

Sollogoub, Matthieu

机构：

[1] Ecole Normale Super, Dept Chim, CNRS, UMR 8642, F-75231 Paris 05, France

[2] Univ Paris 06, Inst Chim Mol, UMR 8642, FR 2769, F-75005 Paris, France

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 25期

关键词：

aluminium; diisobutylaluminium hydride (DIBAL-H); cyclodextrins; selectivity;

D O I：

10.1016/j.tetlet.2006.04.065

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

An expeditious synthesis of a cyclodextrin with three pairs of functionalities on its primary rim is presented. Compared to the previous one, this improved synthetic route yields the product in four steps and 70% yield, instead of six steps and 35% yield; it also bypasses two metathesis reactions and avoids the use of tin reagent. (c) 2006 Elsevier Ltd. All rights reserved.

引用

收藏

页码：4137 / 4139

页数：3

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