Diversity and functions of glycosaminoglycan sulfotransferases

被引：150

作者：

Habuchi, O ^{[1
]}

机构：

[1] Aichi Univ Educ, Dept Life Sci, Kariya, Aichi 4488542, Japan

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS | 2000年 / 1474卷 / 02期

基金：

日本科学技术振兴机构;

关键词：

glycosaminoglycan; sulfotransferase; cloning; substrate specificity; function;

D O I：

10.1016/S0304-4165(00)00016-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Sulfate residues attached to the specific position of the component sugar residues of glycosaminoglycans play important roles in the formation of functional domain structures. The introduction of a sulfate group is catalyzed by various sulfotransferases with strict substrate specificities. A rapid development achieved in the cloning of various glycosaminoglycan sulfotransferases has allowed us to study the biological functions of glycosaminoglycan sulfotransferases and their products, sulfated glycosaminoglycans. (C) 2000 Elsevier Science B.V. All rights reserved.

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页码：115 / 127

页数：13

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