Managing depression across the life cycle: new strategies for clinicians and their patients

被引：21

作者：

Hickie, I. B. ^{[1
]}

Naismith, S. L. ^{[1
]}

Norrie, L. M. ^{[1
]}

Scott, E. M. ^{[1
]}

机构：

[1] Univ Sydney, Brain & Mind Res Inst, Camperdown, NSW 2050, Australia

来源：

INTERNAL MEDICINE JOURNAL | 2009年 / 39卷 / 11期

基金：

澳大利亚国家健康与医学研究理事会;

关键词：

depression; management; antidepressants; early-onset; late-onset; CORONARY-HEART-DISEASE; MAJOR DEPRESSION; CAUDATE-NUCLEUS; OLDER-ADULTS; DEFINING MELANCHOLIA; COGNITIVE IMPAIRMENT; GERIATRIC DEPRESSION; AUSTRALIAN COMMUNITY; HIPPOCAMPAL VOLUMES; PRACTICE GUIDELINES;

D O I：

10.1111/j.1445-5994.2009.02016.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Depression is the leading cause of non-fatal disease burden in Australia. Recently, increasing public recognition, together with the development of more integrated medical and psychological healthcare services has resulted in significant improvements. New pathophysiological models incorporate structural brain changes with established changes in neurotransmitter function. Further, recognition of predisposing factors and the salience of differential ages of onset have led to more pragmatic diagnostic systems. There is an ongoing need to promote early recognition, better information to inform treatment choices and more comprehensive treatment programmes that incorporate behavioural and lifestyle factors in addition to the wide range of pharmacological therapies that are now available.

引用

页码：720 / 727

页数：8

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