Physiopathology and treatment of severe drug eruptions

被引：17

作者：

Bachot, Nicolas ^{[1
]}

Roujeau, Jean-Claude ^{[1
]}

机构：

[1] Univ Paris XII, Serv Dermatol, Hop Henri Mondor, Creteil, France

来源：

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY | 2001年 / 1卷 / 04期

关键词：

D O I：

10.1097/00130832-200108000-00003

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

This review will focus on recent advances concerning the most severe cutaneous drug reactions: the Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reactions with eosinophilia and systemic symptoms. The most significant progress concerned the demonstration that drugs more often than reactive metabolites are immunogenic and induced several kinds of responses. These findings provided the rationale for using new therapeutic approaches, which will be discussed. (C) 2001 Lippincott Williams & Wilkins.

引用

页码：293 / 298

页数：6

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