Highly enantioselective synthesis of β-amino alcohols

被引：32

作者：

Metro, Thomas-Xavier ^{[1
]}

Appenzeller, Jerome ^{[1
]}

Pardo, Domingo Gomez ^{[1
]}

Cossy, Janine ^{[1
]}

机构：

[1] Ecole Super Phys & Chim Ind Ville Paris, Chim Organ Lab, CNRS, F-75231 Paris 05, France

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 16期

关键词：

D O I：

10.1021/ol061133d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N,N-Dialkyl-beta-amino alcohols derived from alpha-amino acids can be rearranged enantiospecifically by using TFAA/Et3N/NaOH to give 1,2-amino alcohols with enantiomeric excess up to 99%.

引用

页码：3509 / 3512

页数：4

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