Chiral ferrocenyl amino alcohols as catalysts for the enantioselective borane reduction of ketones

被引：10

作者：

Brunin, T ^{[1
]}

Cabou, J ^{[1
]}

Bastin, S ^{[1
]}

Brocard, J ^{[1
]}

Pélinski, L ^{[1
]}

机构：

[1] ENSCL, Lab Catalyse Lille, Grp Synth Organomet, CNRS,UMR 8010, F-59652 Villeneuve Dascq, France

来源：

TETRAHEDRON-ASYMMETRY | 2002年 / 13卷 / 12期

关键词：

D O I：

10.1016/S0957-4166(02)00338-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The catalytic asymmetric borane reduction of prochiral ketones was examined in the presence of chiral oxazaborolidine catalysts prepared in situ from chiral ferrocenyl amino alcohols. The corresponding chiral secondary amino alcohols were obtained with modest to high enantiomeric excesses (up to 90%) using (1S,2S)-2-amino-1-ferrocenyl-3,3-dimethyl-1-butanol 5c. (C) 2002 Published by Elsevier Science Ltd.

引用

页码：1241 / 1243

页数：3

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