Nucleotide sequence of the 5' noncoding region of hepatitis G virus isolated from Japanese patients: Comparison with reported isolates

被引：48

作者：

Fukushi, S ^{[1
]}

Kurihara, C ^{[1
]}

Ishiyama, N ^{[1
]}

Okamura, H ^{[1
]}

Hoshino, FB ^{[1
]}

Oya, A ^{[1
]}

Katayama, K ^{[1
]}

机构：

[1] KYORIN UNIV, SCH MED, DEPT INTERNAL MED 3, MITAKA, TOKYO 181, JAPAN

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1996年 / 226卷 / 02期

关键词：

D O I：

10.1006/bbrc.1996.1353

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The nucleotide sequences of the 5' noncoding region (NCR) of hepatitis G virus (HGV) from sera of Japanese patients were determined. Among these isolates, there was a high degree (>96.9%) of sequence identity, whereas identity with previously reported GB virus-C or HGV strains was low (>87.0%). Phylogenetic analyses showed that the HGV strains from Japanese patients clustered in groups distantly separated from previously reported strains. Among the Japanese HGV isolates, the genetic distances corresponded to subtype differences observed within hepatitis C virus (HCV) isolates, whereas the differences between the Japanese isolates and the prototypes corresponded to genetic distances observed between HCV genotypes. The Japanese HGV isolates found in this study should be placed in a new genotype distinct from previously described isolates. (C) 1996 Academic Press, Inc.

引用

页码：314 / 318

页数：5

共 14 条

[1] SEQUENCE-ANALYSIS OF THE 5' NONCODING REGION OF HEPATITIS-C VIRUS [J].

BUKH, J ;

PURCELL, RH ;

MILLER, RH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (11) :4942-4946

[2] USE OF A SIGNATURE NUCLEOTIDE-SEQUENCE OF HEPATITIS-C VIRUS FOR DETECTION OF VIRAL-RNA IN HUMAN SERUM AND PLASMA [J].

CHA, TA ;

KOLBERG, J ;

IRVINE, B ;

STEMPIEN, M ;

BEALL, E ;

YANO, M ;

CHOO, QL ;

HOUGHTON, M ;

KUO, G ;

HAN, JH ;

URDEA, MS .

JOURNAL OF CLINICAL MICROBIOLOGY, 1991, 29 (11) :2528-2534

[3] ANALYSIS OF A NEW HEPATITIS-C VIRUS TYPE AND ITS PHYLOGENETIC RELATIONSHIP TO EXISTING VARIANTS [J].

CHAN, SW ;

MCOMISH, F ;

HOLMES, EC ;

DOW, B ;

PEUTHERER, JF ;

FOLLETT, E ;

YAP, PL ;

SIMMONDS, P .

JOURNAL OF GENERAL VIROLOGY, 1992, 73 :1131-1141

[4] SURVEY OF MAJOR GENOTYPES AND SUBTYPES OF HEPATITIS-C VIRUS USING RFLP OF SEQUENCES AMPLIFIED FROM THE 5' NONCODING REGION [J].

DAVIDSON, F ;

SIMMONDS, P ;

FERGUSON, JC ;

JARVIS, LM ;

DOW, BC ;

FOLLETT, EAC ;

SEED, CRG ;

KRUSIUS, T ;

LIN, C ;

MEDGYESI, GA ;

KIYOKAWA, H ;

OLIM, G ;

DURAISAMY, G ;

CUYPERS, T ;

SAEED, AA ;

TEO, D ;

CONRADIE, J ;

KEW, MC ;

LIN, M ;

NUCHAPRAYOON, C ;

NDIMBIE, OK ;

YAP, PL .

JOURNAL OF GENERAL VIROLOGY, 1995, 76 :1197-1204

[5] COMPLETE 5' NONCODING REGION IS NECESSARY FOR THE EFFICIENT INTERNAL INITIATION OF HEPATITIS-C VIRUS-RNA [J].

FUKUSHI, S ;

KATAYAMA, K ;

KURIHARA, C ;

ISHIYAMA, N ;

HOSHINO, FB ;

ANDO, T ;

OYA, A .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1994, 199 (02) :425-432

[6] QUANTITATIVE DETECTION OF HEPATITIS-C VIRUS-RNA BY MULTICYCLIC RT-PCR [J].

ISHIYAMA, N ;

KATAYAMA, K ;

ISHIMI, N ;

TAKAHASHI, S ;

IGARASHI, H ;

NAKAJIMA, H ;

SAITO, S ;

AOYAGI, T ;

ANDOH, T ;

OYA, A .

INTERNATIONAL HEPATOLOGY COMMUNICATIONS, 1993, 1 (02) :72-79

[7] QUANTIFICATION OF HEPATITIS-C VIRUS BY COMPETITIVE REVERSE TRANSCRIPTION-POLYMERASE CHAIN-REACTION - INCREASE OF THE VIRUS IN ADVANCED LIVER-DISEASE [J].

KATO, N ;

YOKOSUKA, O ;

HOSODA, K ;

ITO, Y ;

OHTO, M ;

OMATA, M .

HEPATOLOGY, 1993, 18 (01) :16-20

[8] SIGNIFICANCE OF SERUM HEPATITIS-C VIRUS-RNA LEVELS IN CHRONIC HEPATITIS-C [J].

LAU, JYN ;

DAVIS, GL ;

KNIFFEN, J ;

QIAN, KP ;

URDEA, MS ;

CHAN, CS ;

MIZOKAMI, M ;

NEUWALD, PD ;

WILBER, JC .

LANCET, 1993, 341 (8859) :1501-1504

[9] Molecular cloning and disease association of hepatitis G virus: A transfusion-transmissible agent [J].

Linnen, J ;

Wages, J ;

ZhangKeck, ZY ;

Fry, KE ;

Krawczynski, KZ ;

Alter, H ;

Koonin, E ;

Gallagher, M ;

Alter, M ;

Hadziyannis, S ;

Karayiannis, P ;

Fung, K ;

Nakatsuji, Y ;

Shih, JWK ;

Young, L ;

Piatak, M ;

Hoover, C ;

Fernandez, J ;

Chen, S ;

Zou, JC ;

Morris, T ;

Hyams, KC ;

Ismay, S ;

Lifson, JD ;

Hess, G ;

Foung, SKH ;

Thomas, H ;

Bradley, D ;

Margolis, H ;

Kim, JP .

SCIENCE, 1996, 271 (5248) :505-508

[10]

OKAMOTO H, 1990, JPN J EXP MED, V60, P167

← 1 2 →