Enzyme biosensor based on surface acoustic wave device

被引：8

作者：

Kondoh, J

Imayama, T

Matsui, Y

Shiokawa, S

机构：

[1] Faculty of Engineering, Shizuoka University, Hamamatsu

[2] Acoustic Society, Japanese Society of Applied Physics

[3] Japanese Society of Applied Physics, Acoustic Society

来源：

ELECTRONICS AND COMMUNICATIONS IN JAPAN PART II-ELECTRONICS | 1996年 / 79卷 / 07期

关键词：

shear horizontal surface wave; acoustoelectric interaction; enzyme sensor; urease; high sensitivity;

D O I：

10.1002/ecjb.4420790708

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

In a shear horizontal surface acoustic wave (SH-SAW) propagating through a piezoelectric crystal, shear wave and piezoelectric potential due to piezoelectric effect are combined. SH-SAW can be useful for chemical sensing in the liquid phase. When the load liquid and propagation surface are in contact, the change in the electrical property of the liquid can be detected due to the acoustoelectric interaction. This paper describes a new type of acoustoelectric biosensor with an enzyme membrane on the SH-SAW propagating plane for detecting pH change in liquid and reports that the SH-SAW enzyme sensor with urease is highly sensitive in detecting urea. In addition, this paper describes the detection limit, aging characteristic, and high sensitivity of the detector.

引用

页码：69 / 75

页数：7

共 12 条

[1]

ANDLE JC, 1993, P 1993 IEEE ULTR S B, P331

[2]

Critchel M., 1978, MED DICT

[3]

FUKAI, 1994, J ACOUSTIC SOC, P1045

[4]

KONDO, 1992, T IEICE, V75, P224

[5]

KONDO, 1994, T IEICE, V77, P338

[6] ENZYME-IMMOBILIZED SH-SAW BIOSENSOR [J].

KONDOH, J ;

MATSUI, Y ;

SHIOKAWA, S ;

WLODARSKI, WB .

SENSORS AND ACTUATORS B-CHEMICAL, 1994, 20 (2-3) :199-203

[7] A SHEAR-HORIZONTAL SAW DEVICE AS A PH MONITOR [J].

KONDOH, J ;

SHIOKAWA, S ;

GEORGIEV, Z .

SENSORS AND ACTUATORS B-CHEMICAL, 1993, 13 (1-3) :429-431

[8]

MORIIZUMI T, 1987, P IEEE ULTR S, P579

[9]

MURAMATSU, 1989, HEREDITY, V43, P25

[10] A LIFT-OFF METHOD FOR PATTERNING ENZYME-IMMOBILIZED MEMBRANES IN MULTI-BIOSENSORS [J].

NAKAMOTO, S ;

ITO, N ;

KURIYAMA, T ;

KIMURA, J .

SENSORS AND ACTUATORS, 1988, 13 (02) :165-172

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