Nutrient sensor links obesity with diabetes risk

被引：46

作者：

Patti, ME ^{[1
]}

Kahn, BB

机构：

[1] Joslin Diabet Ctr, Div Res, Boston, MA 02215 USA

[2] Harvard Univ, Sch Med, Boston, MA 02215 USA

[3] Beth Israel Deaconess Med Ctr, Div Endocrinol Diabet & Metab, Boston, MA 02215 USA

来源：

NATURE MEDICINE | 2004年 / 10卷 / 10期

关键词：

D O I：

10.1038/nm1004-1049

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Overeating can lead to the development of insulin resistance and diabetes. A component of the mTOR nutrient signaling pathway now bridges the mechanistic gap between obesity and insulin resistance.

引用

页码：1049 / 1050

页数：3

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