Enantioselective borane reduction of prochiral ketones catalyzed by a chloro-containing chiral beta-amino alcohol

被引：13

作者：

Shen, ZX

Lu, J

Zhang, Q

Zhang, YW

机构：

[1] Sch. of Chem. and Chem. Engineering, Suzhou University

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 14期

关键词：

D O I：

10.1016/S0957-4166(97)00252-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A chloro-containing chiral beta-amino alcohol (S)-2-amino-3-(2-chlorophenyl)1,1-diphenyl-1-propanol (1) was prepared from the related amino acid, which was synthesized via malonic ester method. As a catalyst for the enantioselective borane reduction of prochiral ketones, 1 is better than those that have a similar structure but have no halogen atom in the molecule. (C) 1997 Elsevier Science Ltd.

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页码：2287 / 2289

页数：3

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